Chemicals and Drugs

Methapyrilene

Histamine H1 antagonist with sedative action used as a hypnotic and in allergies.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Histamine H1 antagonist with sedative action used as a hypnotic and in allergies.

Chemical Identity

Chemical Information

Molecular Formula
C14H19N3S
Molecular Weight
261.39 g/mol
CAS Registry No.
91-80-5
IUPAC Name
N,N-dimethyl-N'-pyridin-2-yl-N'-(thiophen-2-ylmethyl)ethane-1,2-diamine
InChIKey
HNJJXZKZRAWDPF-UHFFFAOYSA-N
SMILES
CN(C)CCN(CC1=CC=CS1)C2=CC=CC=N2
MeSH Unique ID
D008701
Source
PubChem CID 4098

MeSH Record

Classification

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • N,N-Dimethyl-N'-2-pyridinyl-N'-(2-thienylmethyl)-1,2-ethanediamine
  • Thenylpyramine
  • Lullamin
  • Restryl
  • Tenalin
  • Thionylan

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under AMINOPYRIDINES 1979-90; was see under PYRIDINES 1975-78; was see under ANTIHISTAMINICS 1963-74

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Methapyrilene. Medical Subject Headings (MeSH). 2026. Unique ID D008701. http://id.nlm.nih.gov/mesh/2026/D008701
  2. Methapyrilene. In: Wikipedia. https://en.wikipedia.org/wiki/Methapyrilene
  3. Methapyrilene. In: Wikidata. https://www.wikidata.org/wiki/Q59854145
  4. Methapyrilene. In: PubChem Compound. CID 4098. https://pubchem.ncbi.nlm.nih.gov/compound/4098