Structured Summary
Abstract
A phenothiazine with pharmacological activity similar to that of both CHLORPROMAZINE and PROMETHAZINE. It has the histamine-antagonist properties of the antihistamines together with CENTRAL NERVOUS SYSTEM effects resembling those of chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)
Chemical Identity
Chemical Information
- Molecular Formula
- C19H24N2OS
- Molecular Weight
- 328.5 g/mol
- CAS Registry No.
- 60-99-1
- IUPAC Name
- (2R)-3-(2-methoxyphenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine
- InChIKey
- VRQVVMDWGGWHTJ-CQSZACIVSA-N
- SMILES
- C[C@@H](CN1C2=CC=CC=C2SC3=C1C=C(C=C3)OC)CN(C)C
- MeSH Unique ID
- D008728
- Source
- PubChem CID 72287
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
6 entry terms
- Levomeprazin
- Levomepromazine
- Levopromazine
- Tisercin
- Tizercine
- Tizertsin
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
68; was LEVOMEPROMAZINE 1963-67
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Methotrimeprazine. Medical Subject Headings (MeSH). 2026. Unique ID D008728. http://id.nlm.nih.gov/mesh/2026/D008728
- Methotrimeprazine. In: Wikipedia. https://en.wikipedia.org/wiki/Levomepromazine
- Methotrimeprazine. In: Wikidata. https://www.wikidata.org/wiki/Q417204
- Methotrimeprazine. In: PubChem Compound. CID 72287. https://pubchem.ncbi.nlm.nih.gov/compound/72287