Chemicals and Drugs

Mezlocillin

Semisynthetic ampicillin-derived acylureido penicillin. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Semisynthetic ampicillin-derived acylureido penicillin. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections.

Chemical Identity

Chemical Information

Molecular Formula
C21H25N5O8S2
Molecular Weight
539.6 g/mol
CAS Registry No.
51481-65-3
IUPAC Name
(2S,5R,6R)-3,3-dimethyl-6-[[(2R)-2-[(3-methylsulfonyl-2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
InChIKey
YPBATNHYBCGSSN-VWPFQQQWSA-N
SMILES
CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)NC(=O)N4CCN(C4=O)S(=O)(=O)C)C(=O)O)C
MeSH Unique ID
D008802
Source
PubChem CID 656511

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • Meslocillin
  • Mezlocilline
  • Bay-f 1353
  • Baypen
  • Melocin
  • Mezlin
  • Mezlocillin Sodium
  • Bay f 1353
  • Bayf 1353
  • Sodium, Mezlocillin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

84

MeSH Record

Previous Indexing

  • Penicillins (1966-1983)

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.589w.099w.750w.750w.050w.500w
  2. D02w.886w.108w.750w.750w.050w.500w
  3. D03w.633.100.300w.750w.750w.050w.500w

AMA Style

References

  1. National Library of Medicine. Mezlocillin. Medical Subject Headings (MeSH). 2026. Unique ID D008802. http://id.nlm.nih.gov/mesh/2026/D008802
  2. Mezlocillin. In: Wikipedia. https://en.wikipedia.org/wiki/Mezlocillin
  3. Mezlocillin. In: Wikidata. https://www.wikidata.org/wiki/Q3307752
  4. Mezlocillin. In: PubChem Compound. CID 656511. https://pubchem.ncbi.nlm.nih.gov/compound/656511