Organisms

Mink Cell Focus-Inducing Viruses

Strains of MURINE LEUKEMIA VIRUS discovered in 1976 by Hartley, Wolford, Old, and Rowe and so named because the viruses originally isolated had the capacity to transform cell foci in mink cell cultures. MCF viruses are generated by recombination with ecotropic murine leukemia viruses including AKR, Friend, Moloney, and Rauscher, causing ERYTHROLEUKEMIA and severe anemia in mice.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Strains of MURINE LEUKEMIA VIRUS discovered in 1976 by Hartley, Wolford, Old, and Rowe and so named because the viruses originally isolated had the capacity to transform cell foci in mink cell cultures. MCF viruses are generated by recombination with ecotropic murine leukemia viruses including AKR, Friend, Moloney, and Rauscher, causing ERYTHROLEUKEMIA and severe anemia in mice.

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Classification

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Synonyms

7 entry terms
  • MCF Viruses
  • Mink cell focus-inducing virus
  • MCF Virus
  • Mink Cell Focus Inducing Viruses
  • Mink cell focus inducing virus
  • Virus, MCF
  • Viruses, MCF

MeSH Record

Aspects Covered

13 allowable subheadings

Indexed with the subheadings chemistry, classification, drug effects, enzymology, genetics, growth & development, immunology, isolation & purification, metabolism, pathogenicity, physiology, radiation effects, ultrastructure.

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Indexing Annotation

infection: coordinate IM with RETROVIRIDAE INFECTIONS (IM) + TUMOR VIRUS INFECTIONS (IM); add also LEUKEMIA, EXPERIMENTAL (IM), or LEUKEMIA (IM) (for spontaneous leukemia), or ERYTHROLEUKEMIA (IM) if pertinent

MeSH Record

History Note

91(86); was see under MOUSE LEUKEMIA VIRUSES 1986-90

MeSH Record

Previous Indexing

  • Friend Virus (1966-1985)
  • Leukemia, Experimental (1966-1985)
  • Mouse Leukemia Viruses (1966-1985)

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References

  1. National Library of Medicine. Mink Cell Focus-Inducing Viruses. Medical Subject Headings (MeSH). 2026. Unique ID D008908. http://id.nlm.nih.gov/mesh/2026/D008908
  2. Mink Cell Focus-Inducing Viruses. In: Wikidata. https://www.wikidata.org/wiki/Q69344671