Diseases

Multiple Endocrine Neoplasia

A group of autosomal dominant diseases characterized by the combined occurrence of tumors involving two or more ENDOCRINE GLANDS that secrete PEPTIDE HORMONES or AMINES. These neoplasias are often benign but can be malignant. They are classified by the endocrine glands involved and the degree of aggressiveness. The two major forms are MEN1 and MEN2 with gene mutations on CHROMOSOME 11 and CHROMOSOME 10, respectively.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A group of autosomal dominant diseases characterized by the combined occurrence of tumors involving two or more ENDOCRINE GLANDS that secrete PEPTIDE HORMONES or AMINES. These neoplasias are often benign but can be malignant. They are classified by the endocrine glands involved and the degree of aggressiveness. The two major forms are MEN1 and MEN2 with gene mutations on CHROMOSOME 11 and CHROMOSOME 10, respectively.

MeSH Record

Classification

Broader headings

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MeSH Record

See Also

MeSH Record

Synonyms

25 entry terms
  • Adenomatosis, Familial Endocrine
  • Adenomatosis, Multiple Endocrine
  • Endocrine Neoplasia, Multiple
  • Familial Endocrine Adenomatosis
  • Multiple Endocrine Adenomatosis
  • Multiple Endocrine Adenopathy
  • Multiple Endocrine Neoplasia Syndrome
  • Multiple Endocrine Neoplasia Syndromes
  • Multiple Endocrine Neoplasms
  • Neoplasia, Multiple Endocrine
  • Neoplasms, Multiple Endocrine
  • Adenomatoses, Familial Endocrine
  • Adenomatoses, Multiple Endocrine
  • Adenopathies, Multiple Endocrine
  • Adenopathy, Multiple Endocrine
  • Endocrine Adenomatoses, Familial
  • Endocrine Adenomatoses, Multiple
  • Endocrine Adenomatosis, Familial
  • Endocrine Adenomatosis, Multiple
  • Endocrine Adenopathies, Multiple
  • Endocrine Adenopathy, Multiple
  • Endocrine Neoplasms, Multiple
  • Familial Endocrine Adenomatoses
  • Multiple Endocrine Adenomatoses
  • Multiple Endocrine Adenopathies

MeSH Record

Aspects Covered

39 allowable subheadings

Indexed with the subheadings blood, blood supply, cerebrospinal fluid, chemically induced, chemistry, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, secondary, surgery, therapy, ultrastructure, urine, veterinary, virology.

MeSH Record

Indexing Annotation

general or unspecified; prefer specifics; coordinate IM with specific endocrine/neoplasm pre-coordinates (IM) + specific histological type (IM) if pertinent

MeSH Record

History Note

95; was NEOPLASMS, MULTIPLE ENDOCRINE 1983-94; was ADENOMATOSIS, FAMILIAL ENDOCRINE 1965-82 (Prov 1964)

MeSH Hierarchy

Tree Numbers

  1. C04w.588.322w.400w
  2. C04w.651.600w
  3. C04w.700w.630w
  4. C16w.320w.700w.630w
  5. C19w.344w.400w

MeSH Record

NLM Classification

WK 145

AMA Style

References

  1. National Library of Medicine. Multiple Endocrine Neoplasia. Medical Subject Headings (MeSH). 2026. Unique ID D009377. http://id.nlm.nih.gov/mesh/2026/D009377
  2. Multiple Endocrine Neoplasia. In: Wikipedia. https://en.wikipedia.org/wiki/Multiple_endocrine_neoplasia
  3. Multiple Endocrine Neoplasia. In: Wikidata. https://www.wikidata.org/wiki/Q1553018