Chemicals and Drugs

N-Methylaspartate

An amino acid that, as the D-isomer, is the defining agonist for the NMDA receptor subtype of glutamate receptors (RECEPTORS, NMDA).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An amino acid that, as the D-isomer, is the defining agonist for the NMDA receptor subtype of glutamate receptors (RECEPTORS, NMDA).

Chemical Identity

Chemical Information

Molecular Formula
C5H9NO4
Molecular Weight
147.13 g/mol
CAS Registry No.
6384-92-5
IUPAC Name
(2R)-2-(methylamino)butanedioic acid
InChIKey
HOKKHZGPKSLGJE-GSVOUGTGSA-N
SMILES
CN[C@H](CC(=O)O)C(=O)O
MeSH Unique ID
D016202
Source
PubChem CID 22880

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

See Also

MeSH Record

Synonyms

7 entry terms
  • N-Methyl-D-aspartate
  • N-Methyl-D-aspartic Acid
  • NMDA
  • Acid, N-Methyl-D-aspartic
  • N Methyl D aspartate
  • N Methyl D aspartic Acid
  • N Methylaspartate

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91

MeSH Record

Previous Indexing

  • Aspartic Acid (1966-1990)
  • Convulsants (1975-1990)

MeSH Hierarchy

Tree Numbers

  1. D12.125w.067.500.400w
  2. D12.125w.119.170.400w

AMA Style

References

  1. National Library of Medicine. N-Methylaspartate. Medical Subject Headings (MeSH). 2026. Unique ID D016202. http://id.nlm.nih.gov/mesh/2026/D016202
  2. N-Methylaspartate. In: Wikipedia. https://en.wikipedia.org/wiki/N-Methyl-D-aspartic_acid
  3. N-Methylaspartate. In: Wikidata. https://www.wikidata.org/wiki/Q632856
  4. N-Methylaspartate. In: PubChem Compound. CID 22880. https://pubchem.ncbi.nlm.nih.gov/compound/22880