Chemicals and Drugs

NADP-dependent Hydroxymethylglutaryl-CoA-Reductases

Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. In liver enzymes of this class are involved in cholesterol biosynthesis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. In liver enzymes of this class are involved in cholesterol biosynthesis.

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Classification

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MeSH Record

Synonyms

9 entry terms
  • 3-Hydroxy-3-methylglutaryl-coenzyme A reductase, NADP-dependent
  • HMG CoA-Reductases, NADP-Dependent
  • Hydroxymethylglutaryl-CoA-Reductase (NADP)
  • Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent
  • Hydroxymethylglutaryl-Coenzyme A Reductase (NADP)
  • 3 Hydroxy 3 methylglutaryl coenzyme A reductase, NADP dependent
  • CoA-Reductases, NADP-Dependent HMG
  • HMG CoA Reductases, NADP Dependent
  • NADP-Dependent HMG CoA-Reductases

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

do not confuse with HYDROXYMETHYLGLUTARYL-COA REDUCTASES, NAD-DEPENDENT

MeSH Record

History Note

2002; use HYDROXYMETHYLGLUTARYL COA REDUCTASES (NM) 1981-2001

MeSH Record

Previous Indexing

  • Hydroxymethylglutaryl CoA Reductases (1987-2001)

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AMA Style

References

  1. National Library of Medicine. NADP-dependent Hydroxymethylglutaryl-CoA-Reductases. Medical Subject Headings (MeSH). 2026. Unique ID D025782. http://id.nlm.nih.gov/mesh/2026/D025782
  2. NADP-dependent Hydroxymethylglutaryl-CoA-Reductases. In: Wikipedia. https://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_reductase_(NADPH)
  3. NADP-dependent Hydroxymethylglutaryl-CoA-Reductases. In: Wikidata. https://www.wikidata.org/wiki/Q2330287