Chemicals and Drugs

Hydroxymethylglutaryl CoA Reductases

Enzymes that catalyze the reversible reduction of alpha-carboxyl group of 3-hydroxy-3-methylglutaryl-coenzyme A to yield MEVALONIC ACID.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Enzymes that catalyze the reversible reduction of alpha-carboxyl group of 3-hydroxy-3-methylglutaryl-coenzyme A to yield MEVALONIC ACID.

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Classification

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See Also

MeSH Record

Synonyms

7 entry terms
  • 3-Hydroxy-3-methylglutaryl CoA Reductase
  • HMG CoA Reductase
  • HMG CoA Reductases
  • Hydroxymethylglutaryl CoA Reductase
  • 3 Hydroxy 3 methylglutaryl CoA Reductase
  • CoA Reductase, 3-Hydroxy-3-methylglutaryl
  • Reductase, 3-Hydroxy-3-methylglutaryl CoA

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

78(75); was see under ALCOHOL OXIDOREDUCTASES 1975-77

MeSH Record

Previous Indexing

  • Alcohol Oxidoreductases (1966-1977)
  • Glutarates (1966-1974)
  • Mevalonic Acid (1966-1974)

MeSH Hierarchy

Tree Number

MeSH Record

NLM Classification

QU 140

AMA Style

References

  1. National Library of Medicine. Hydroxymethylglutaryl CoA Reductases. Medical Subject Headings (MeSH). 2026. Unique ID D006903. http://id.nlm.nih.gov/mesh/2026/D006903
  2. Hydroxymethylglutaryl CoA Reductases. In: Wikidata. https://www.wikidata.org/wiki/Q76385166