Structured Summary
Abstract
A voltage-gated sodium channel subtype that mediates the sodium ion permeability of excitable membranes. Defects in the SCN2A gene which codes for the alpha subunit of this sodium channel are associated with benign familial infantile seizures type 3, and early infantile epileptic encephalopathy type 11.
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Classification
Broader headings
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MeSH Record
Synonyms
14 entry terms
- Type 2 Voltage-Gated Sodium Channel
- Voltage-Gated Sodium Channel Type 2
- NAV1.2 Voltage Gated Sodium Channel
- Type 2 Voltage Gated Sodium Channel
- Voltage Gated Sodium Channel Type 2
- NAV1.2 alpha Subunit
- SCN2A Sodium Channel alpha Subunit
- Sodium Channel Protein Type 2 Subunit alpha
- Sodium Channel, Voltage-Gated, Type II, alpha 1
- Sodium Channel, Voltage-Gated, Type II, alpha 1 Subunit
- Voltage-Gated Sodium Channel Type 2 Subunit alpha
- Voltage-Gated Sodium Channel Type 2 alpha Subunit
- Voltage Gated Sodium Channel Type 2 Subunit alpha
- Voltage Gated Sodium Channel Type 2 alpha Subunit
MeSH Record
Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2013
MeSH Record
Previous Indexing
- Sodium Channels (1989-2012)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. NAV1.2 Voltage-Gated Sodium Channel. Medical Subject Headings (MeSH). 2026. Unique ID D062551. http://id.nlm.nih.gov/mesh/2026/D062551
- NAV1.2 Voltage-Gated Sodium Channel. In: Wikidata. https://www.wikidata.org/wiki/Q21135448