Chemicals and Drugs

Voltage-Gated Sodium Channels

A family of membrane proteins that selectively conduct SODIUM ions due to changes in the TRANSMEMBRANE POTENTIAL DIFFERENCE. They typically have a multimeric structure with a core alpha subunit that defines the sodium channel subtype and several beta subunits that modulate sodium channel activity.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of membrane proteins that selectively conduct SODIUM ions due to changes in the TRANSMEMBRANE POTENTIAL DIFFERENCE. They typically have a multimeric structure with a core alpha subunit that defines the sodium channel subtype and several beta subunits that modulate sodium channel activity.

MeSH Record

Classification

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MeSH Record

Synonyms

8 entry terms
  • Sodium Channels, Voltage-Gated
  • Voltage-Gated Sodium Channel
  • Channel, Voltage-Gated Sodium
  • Channels, Voltage-Gated Sodium
  • Sodium Channel, Voltage-Gated
  • Sodium Channels, Voltage Gated
  • Voltage Gated Sodium Channel
  • Voltage Gated Sodium Channels

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

general or unspecified; prefer specifics

MeSH Record

History Note

2013

MeSH Record

Previous Indexing

  • Sodium Channels (1989-2012)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Voltage-Gated Sodium Channels. Medical Subject Headings (MeSH). 2026. Unique ID D061566. http://id.nlm.nih.gov/mesh/2026/D061566
  2. Voltage-Gated Sodium Channels. In: Wikidata. https://www.wikidata.org/wiki/Q14905705