Chemicals and Drugs

NF-kappa B

Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.

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Classification

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MeSH Record

Synonyms

21 entry terms
  • Immunoglobulin Enhancer-Binding Protein
  • NF-kB
  • NF-kappaB
  • Nuclear Factor kappa B
  • Nuclear Factor-Kappab
  • Transcription Factor NF-kB
  • kappa B Enhancer Binding Protein
  • Enhancer-Binding Protein, Immunoglobulin
  • Factor NF-kB, Transcription
  • Factor-Kappab, Nuclear
  • Immunoglobulin Enhancer Binding Protein
  • NF kB
  • NF kappaB
  • NF-kB, Transcription Factor
  • Nuclear Factor Kappab
  • Transcription Factor NF kB
  • Ig-EBP-1
  • NF-kappa B Complex
  • Complex, NF-kappa B
  • Ig EBP 1
  • NF kappa B Complex

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

91

MeSH Record

Previous Indexing

  • DNA-Binding Proteins (1987-1990)
  • Transcription Factors (1987-1990)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. NF-kappa B. Medical Subject Headings (MeSH). 2026. Unique ID D016328. http://id.nlm.nih.gov/mesh/2026/D016328
  2. NF-kappa B. In: Wikipedia. https://en.wikipedia.org/wiki/NF-%CE%BAB
  3. NF-kappa B. In: Wikidata. https://www.wikidata.org/wiki/Q411114