Structured Summary
Abstract
A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.
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Synonyms
5 entry terms
- I kappa B
- I-kappa B
- IkB DNA-Binding Proteins
- I kappa B Proteins
- IkB DNA Binding Proteins
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
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History Note
2006(2000)
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Previous Indexing
- DNA-Binding Proteins (1998-1999)
- Proto-Oncogene Proteins (1993-1998)
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References
- National Library of Medicine. I-kappa B Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D020672. http://id.nlm.nih.gov/mesh/2026/D020672
- I-kappa B Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q78128308