Chemicals and Drugs

Neurokinin-1 Receptors

A class of cell surface receptors for TACHYKININS with a preference for SUBSTANCE P. Neurokinin-1 (NK-1) receptors have been cloned and are members of the G protein coupled receptor superfamily. They are found on many cell types including central and peripheral neurons, smooth muscle cells, acinar cells, endothelial cells, fibroblasts, and immune cells.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A class of cell surface receptors for TACHYKININS with a preference for SUBSTANCE P. Neurokinin-1 (NK-1) receptors have been cloned and are members of the G protein coupled receptor superfamily. They are found on many cell types including central and peripheral neurons, smooth muscle cells, acinar cells, endothelial cells, fibroblasts, and immune cells.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

See Also

MeSH Record

Synonyms

29 entry terms
  • NK-1 Receptor
  • NK-1 Receptors
  • Neurokinin-1 Receptor
  • Receptors, NK-1
  • Receptors, Neurokinin-1
  • Receptors, SP-P
  • Receptors, Substance P
  • SP-P Receptor
  • SP-P Receptors
  • Substance P Receptor
  • Substance P Receptors
  • Substance-P Receptor
  • Tachykinin Receptor 1
  • NK 1 Receptor
  • NK 1 Receptors
  • Neurokinin 1 Receptor
  • Neurokinin 1 Receptors
  • P Receptor, Substance
  • P Receptors, Substance
  • Receptor, NK-1
  • Receptor, Neurokinin-1
  • Receptor, SP-P
  • Receptor, Substance P
  • Receptor, Substance-P
  • Receptors, NK 1
  • Receptors, Neurokinin 1
  • Receptors, SP P
  • SP P Receptor
  • SP P Receptors

MeSH Record

Aspects Covered

18 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

94; was SUBSTANCE P RECEPTOR (NM) 1981-93; NK-1 RECEPTOR & NEUROKININ-1 RECEPTOR were SY to SUBSTANCE K RECEPTOR 1986-93; NK-1 RECEPTOR SITE was SY to TACHYKININ RECEPTOR 1989-93

MeSH Record

Previous Indexing

  • Receptors, Cell Surface (1981-1984)
  • Receptors, Drug (1968-1993)
  • Receptors, Neurotransmitter (1985-1993)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.543w.750w.695w.862w.500
  2. D12.776w.543w.750w.720w.600w.830w.500
  3. D12.776w.543w.750w.750w.555w.830w.500

AMA Style

References

  1. National Library of Medicine. Neurokinin-1 Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D018040. http://id.nlm.nih.gov/mesh/2026/D018040
  2. Neurokinin-1 Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q24784548