Chemicals and Drugs

Non-Receptor Type 1 Protein Tyrosine Phosphatase

A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting motifs; an N-terminal motif specific for the INSULIN RECEPTOR, and a C-terminal motif specific for the SH3 domain containing proteins. This subtype includes a hydrophobic domain which localizes it to the ENDOPLASMIC RETICULUM.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting motifs; an N-terminal motif specific for the INSULIN RECEPTOR, and a C-terminal motif specific for the SH3 domain containing proteins. This subtype includes a hydrophobic domain which localizes it to the ENDOPLASMIC RETICULUM.

MeSH Record

Classification

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MeSH Record

Synonyms

7 entry terms
  • PTPase 1B
  • PTPase HA2
  • Protein Tyrosine Phosphatase 1B
  • Protein Tyrosine Phosphatase, Non-Receptor Type 1
  • Protein-Tyrosine Phosphatase HA2
  • Protein Tyrosine Phosphatase HA2
  • Protein Tyrosine Phosphatase, Non Receptor Type 1

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2008

MeSH Record

Previous Indexing

  • Protein Tyrosine Phosphatases (1991-2007)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Non-Receptor Type 1 Protein Tyrosine Phosphatase. Medical Subject Headings (MeSH). 2026. Unique ID D054562. http://id.nlm.nih.gov/mesh/2026/D054562
  2. Non-Receptor Type 1 Protein Tyrosine Phosphatase. In: Wikidata. https://www.wikidata.org/wiki/Q21171691