Chemicals and Drugs

Non-Receptor Type 2 Protein Tyrosine Phosphatase

A subtype of non-receptor protein tyrosine phosphatase that is closely-related to PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1. Alternative splicing of the mRNA for this phosphatase results in the production at two gene products, one of which includes a C-terminal nuclear localization domain that may be involved in the transport of the protein to the CELL NUCLEUS. Although initially referred to as T-cell protein tyrosine phosphatase the expression of this subtype occurs widely.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A subtype of non-receptor protein tyrosine phosphatase that is closely-related to PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1. Alternative splicing of the mRNA for this phosphatase results in the production at two gene products, one of which includes a C-terminal nuclear localization domain that may be involved in the transport of the protein to the CELL NUCLEUS. Although initially referred to as T-cell protein tyrosine phosphatase the expression of this subtype occurs widely.

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Classification

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MeSH Record

Synonyms

12 entry terms
  • Protein Tyrosine Phosphatase, Non-Receptor Type 2
  • T-Cell Protein Tyrosine Phosphatase
  • TC-PTP
  • TCPTP Enzyme
  • Protein Tyrosine Phosphatase, Non Receptor Type 2
  • T Cell Protein Tyrosine Phosphatase
  • Protein Tyrosine Phosphatase, Non-Receptor Type 2, TC45 Isoform
  • Protein Tyrosine Phosphatase, Non-Receptor Type 2, TC48 Isoform
  • TC45 Enzyme
  • TC45 Protein Tyrosine Phosphatase
  • TC48 Enzyme
  • TC48 Protein Tyrosine Phosphatase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2008(1994)

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AMA Style

References

  1. National Library of Medicine. Non-Receptor Type 2 Protein Tyrosine Phosphatase. Medical Subject Headings (MeSH). 2026. Unique ID D054578. http://id.nlm.nih.gov/mesh/2026/D054578
  2. Non-Receptor Type 2 Protein Tyrosine Phosphatase. In: Wikidata. https://www.wikidata.org/wiki/Q21171735