Structured Summary
Abstract
A nuclear receptor coactivator with specificity for ESTROGEN RECEPTORS and PROGESTERONE RECEPTORS. It contains a histone acetyltransferase activity that may play a role in CHROMATIN REMODELING during the process of nuclear receptor-induced transcription. The coactivator has been found at elevated levels in certain HORMONE-DEPENDENT NEOPLASMS such as those found in BREAST CANCER.
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Synonyms
7 entry terms
- Amplified in Breast Cancer-1 Protein
- Nuclear Receptor Coactivator-3
- Receptor-Associated Coactivator 3
- Steroid Receptor Coactivator 3
- Thyroid Hormone Receptor Activator Molecule 1
- Amplified in Breast Cancer 1 Protein
- Receptor Associated Coactivator 3
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2010(1997)
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References
- National Library of Medicine. Nuclear Receptor Coactivator 3. Medical Subject Headings (MeSH). 2026. Unique ID D056921. http://id.nlm.nih.gov/mesh/2026/D056921
- Nuclear Receptor Coactivator 3. In: Wikidata. https://www.wikidata.org/wiki/Q24779790