Structured Summary
Abstract
Double-stranded nucleic acid molecules (DNA-DNA or DNA-RNA) which contain regions of nucleotide mismatches (non-complementary). In vivo, these heteroduplexes can result from mutation or genetic recombination; in vitro, they are formed by nucleic acid hybridization. Electron microscopic analysis of the resulting heteroduplexes facilitates the mapping of regions of base sequence homology of nucleic acids.
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Synonyms
4 entry terms
- Heteroduplexes, Nucleic Acid
- Acid Heteroduplexes, Nucleic
- Heteroduplex DNA
- DNA, Heteroduplex
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
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Indexing Annotation
coord with specific DNA or RNA or both (IM)
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History Note
80
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Previous Indexing
- Base Sequence (1971-1979)
- DNA (1966-1979)
- Mutation (1966-1979)
- Nucleic Acid Hybridization (1971-1979)
- RNA (1966-1979)
- Recombination, Genetic (1968-1979)
- specific DNA (1966-1979)
- specific RNA (1966-1979)
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References
- National Library of Medicine. Nucleic Acid Heteroduplexes. Medical Subject Headings (MeSH). 2026. Unique ID D009692. http://id.nlm.nih.gov/mesh/2026/D009692
- Nucleic Acid Heteroduplexes. In: Wikipedia. https://en.wikipedia.org/wiki/Heteroduplex
- Nucleic Acid Heteroduplexes. In: Wikidata. https://www.wikidata.org/wiki/Q408140