Structured Summary
Abstract
Transforming proteins encoded by erbB oncogenes from the avian erythroblastosis virus. The protein is a truncated form of the EGF receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR) whose kinase domain is constitutively activated by deletion of the ligand-binding domain.
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Synonyms
7 entry terms
- Oncogene Products v-erbB
- Oncogene Proteins erbB
- erbB Oncogene Proteins
- v-erbB Proteins
- Oncogene Products v erbB
- Oncogene Proteins v erbB
- v erbB Proteins
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
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Indexing Annotation
coordinate with specific virus
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History Note
95; was ONCOGENE PROTEINS ERBB (NM) 1987-94
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Previous Indexing
- Oncogene Proteins, Viral (1988-1994)
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AMA Style
References
- National Library of Medicine. Oncogene Proteins v-erbB. Medical Subject Headings (MeSH). 2026. Unique ID D018739. http://id.nlm.nih.gov/mesh/2026/D018739
- Oncogene Proteins v-erbB. In: Wikidata. https://www.wikidata.org/wiki/Q58622090