Diseases

Optic Nerve Diseases

Conditions which produce injury or dysfunction of the second cranial or optic nerve, which is generally considered a component of the central nervous system. Damage to optic nerve fibers may occur at or near their origin in the retina, at the optic disk, or in the nerve, optic chiasm, optic tract, or lateral geniculate nuclei. Clinical manifestations may include decreased visual acuity and contrast sensitivity, impaired color vision, and an afferent pupillary defect.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Conditions which produce injury or dysfunction of the second cranial or optic nerve, which is generally considered a component of the central nervous system. Damage to optic nerve fibers may occur at or near their origin in the retina, at the optic disk, or in the nerve, optic chiasm, optic tract, or lateral geniculate nuclei. Clinical manifestations may include decreased visual acuity and contrast sensitivity, impaired color vision, and an afferent pupillary defect.

MeSH Record

Classification

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MeSH Record

Synonyms

21 entry terms
  • Cranial Nerve II Diseases
  • Cranial Nerve II Disorder
  • Neural-Optical Lesion
  • Optic Neuropathy
  • Second Cranial Nerve Diseases
  • Lesion, Neural-Optical
  • Neural Optical Lesion
  • Neural-Optical Lesions
  • Neuropathy, Optic
  • Optic Nerve Disease
  • Optic Neuropathies
  • Foster-Kennedy Syndrome
  • Optic Disc Disorders
  • Optic Disk Disorders
  • Disc Disorder, Optic
  • Disk Disorder, Optic
  • Disorder, Optic Disc
  • Foster Kennedy Syndrome
  • Optic Disc Disorder
  • Optic Disk Disorder
  • Syndrome, Foster-Kennedy

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

Indexing Annotation

SMON: see note on OPTIC NEURITIS; inflamm dis = OPTIC NEURITIS

MeSH Record

History Note

76; was NON MESH before 1976

MeSH Record

Previous Indexing

  • Optic Nerve (1966-1975)

MeSH Hierarchy

Tree Numbers

  1. C10w.292w.700w
  2. C11w.640w

MeSH Record

NLM Classification

WW 280

AMA Style

References

  1. National Library of Medicine. Optic Nerve Diseases. Medical Subject Headings (MeSH). 2026. Unique ID D009901. http://id.nlm.nih.gov/mesh/2026/D009901
  2. Optic Nerve Diseases. In: Wikipedia. https://en.wikipedia.org/wiki/Optic_neuropathy
  3. Optic Nerve Diseases. In: Wikidata. https://www.wikidata.org/wiki/Q2879095