Structured Summary
Abstract
A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B.
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Classification
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Synonyms
9 entry terms
- FDCR-1 Protein
- Follicular Dendritic Cell-Derived Receptor-1
- OCIF Protein
- Osteoclastogenesis Inhibitory Factor
- Receptors, Tumor Necrosis Factor, Member 11b
- Tumor Necrosis Factor Receptor 11b
- Tumor Necrosis Factor Receptor Superfamily, Member 11b
- FDCR 1 Protein
- Follicular Dendritic Cell Derived Receptor 1
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2007(1997)
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AMA Style
References
- National Library of Medicine. Osteoprotegerin. Medical Subject Headings (MeSH). 2026. Unique ID D053244. http://id.nlm.nih.gov/mesh/2026/D053244
- Osteoprotegerin. In: Wikipedia. https://en.wikipedia.org/wiki/Osteoprotegerin
- Osteoprotegerin. In: Wikidata. https://www.wikidata.org/wiki/Q3357478