Chemicals and Drugs

PAR-1 Receptor

A thrombin receptor subtype that couples to HETEROTRIMERIC GTP-BINDING PROTEINS resulting in the activation of a variety of signaling mechanisms including decreased intracellular CYCLIC AMP, increased TYPE C PHOSPHOLIPASES and increased PHOSPHOLIPASE A2.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A thrombin receptor subtype that couples to HETEROTRIMERIC GTP-BINDING PROTEINS resulting in the activation of a variety of signaling mechanisms including decreased intracellular CYCLIC AMP, increased TYPE C PHOSPHOLIPASES and increased PHOSPHOLIPASE A2.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

9 entry terms
  • PAR1 Receptor
  • Protease-Activated Receptor 1
  • Proteinase-Activated Receptor 1
  • Receptor, PAR-1
  • PAR 1 Receptor
  • Protease Activated Receptor 1
  • Proteinase Activated Receptor 1
  • Receptor, PAR 1
  • Receptor, PAR1

MeSH Record

Aspects Covered

18 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2004; use RECEPTOR, PROTEINASE-ACTIVATED 1 (NM) 1997-2003

MeSH Record

Previous Indexing

  • Receptors, Thrombin (1997-2003)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.890w.625w.800w.790w
  2. D12.776w.395w.550w.625w.800w.790w
  3. D12.776w.543w.550w.625w.800w.790w
  4. D12.776w.543w.750w.695w.875w.500w
  5. D12.776w.543w.750w.705w.675w.892w.790w
  6. D12.776w.543w.750w.750w.850w.399w
  7. D12.776w.543w.750w.792w.500w.500w

AMA Style

References

  1. National Library of Medicine. PAR-1 Receptor. Medical Subject Headings (MeSH). 2026. Unique ID D044463. http://id.nlm.nih.gov/mesh/2026/D044463
  2. PAR-1 Receptor. In: Wikipedia. https://en.wikipedia.org/wiki/Proteinase-activated_receptor_1
  3. PAR-1 Receptor. In: Wikidata. https://www.wikidata.org/wiki/Q21106737