Anatomy

PC12 Cells

A CELL LINE derived from a PHEOCHROMOCYTOMA of the rat ADRENAL MEDULLA. PC12 cells stop dividing and undergo terminal differentiation when treated with NERVE GROWTH FACTOR, making the line a useful model system for NERVE CELL differentiation.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A CELL LINE derived from a PHEOCHROMOCYTOMA of the rat ADRENAL MEDULLA. PC12 cells stop dividing and undergo terminal differentiation when treated with NERVE GROWTH FACTOR, making the line a useful model system for NERVE CELL differentiation.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

5 entry terms
  • Pheochromocytoma Cell Line
  • Cell Line, Pheochromocytoma
  • Cell Lines, Pheochromocytoma
  • PC12 Cell
  • Pheochromocytoma Cell Lines

MeSH Record

Aspects Covered

15 allowable subheadings

Indexed with the subheadings chemistry, classification, cytology, drug effects, enzymology, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.

MeSH Record

Indexing Annotation

PC stands for PheochromoCytoma; almost always NIM with no subheadings; check ANIMAL; & RATS; do not routinely add PHEOCHROMOCYTOMA or ADRENAL GLAND NEOPLASMS

MeSH Record

History Note

92

MeSH Record

Previous Indexing

  • Cell Line (1976-1991)
  • Clone Cells (1977-1987)
  • Tumor Cells, Cultured (1987-1991)

MeSH Hierarchy

Tree Numbers

  1. A11w.251.210w.190.750w
  2. A11w.251.860.180.750w
  3. A11w.299w.500w

AMA Style

References

  1. National Library of Medicine. PC12 Cells. Medical Subject Headings (MeSH). 2026. Unique ID D016716. http://id.nlm.nih.gov/mesh/2026/D016716
  2. PC12 Cells. In: Wikipedia. https://en.wikipedia.org/wiki/PC12_cell_line
  3. PC12 Cells. In: Wikidata. https://www.wikidata.org/wiki/Q7118481