Structured Summary
Abstract
Abnormal immunoglobulins synthesized by atypical cells of the MONONUCLEAR PHAGOCYTE SYSTEM. Paraproteins containing only light chains lead to Bence Jones paraproteinemia, while the presence of only atypical heavy chains leads to heavy chain disease. Most of the paraproteins show themselves as an M-component (monoclonal gammopathy) in electrophoresis. Diclonal and polyclonal paraproteins are much less frequently encountered.
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Synonyms
1 entry terms
- Paraprotein
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Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
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History Note
76; was see under GLOBULINS 1963-65
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Previous Indexing
- Blood Protein Disorders (1966-1975)
- Immunoglobulins (1970-1975)
- specific immunoglobulin (1966-1975)
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NLM Classification
QW 601
AMA Style
References
- National Library of Medicine. Paraproteins. Medical Subject Headings (MeSH). 2026. Unique ID D010266. http://id.nlm.nih.gov/mesh/2026/D010266
- Paraproteins. In: Wikipedia. https://en.wikipedia.org/wiki/Paraprotein
- Paraproteins. In: Wikidata. https://www.wikidata.org/wiki/Q417500