Chemicals and Drugs

Paroxetine

A serotonin uptake inhibitor that is effective in the treatment of depression.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A serotonin uptake inhibitor that is effective in the treatment of depression.

Chemical Identity

Chemical Information

Molecular Formula
C19H20FNO3
Molecular Weight
329.4 g/mol
CAS Registry No.
61869-08-7
IUPAC Name
(3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine
InChIKey
AHOUBRCZNHFOSL-YOEHRIQHSA-N
SMILES
C1CNC[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4
MeSH Unique ID
D017374
Source
PubChem CID 43815

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

18 entry terms
  • Aropax
  • BRL-29060
  • FG-7051
  • Paroxetine Acetate
  • Paroxetine Hydrochloride
  • Paroxetine Hydrochloride Anhydrous
  • Paroxetine Hydrochloride Hemihydrate
  • Paroxetine Hydrochloride, Hemihydrate
  • Paroxetine Maleate
  • Paroxetine, cis-(+)-Isomer
  • Paroxetine, cis-(-)-Isomer
  • Paroxetine, trans-(+)-Isomer
  • Paxil
  • Seroxat
  • BRL 29060
  • BRL29060
  • FG 7051
  • FG7051

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

1993 (1978)

MeSH Record

Previous Indexing

  • Dioxolanes (1978-1982)
  • Piperidines (1982-1992)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Paroxetine. Medical Subject Headings (MeSH). 2026. Unique ID D017374. http://id.nlm.nih.gov/mesh/2026/D017374
  2. Paroxetine. In: Wikipedia. https://en.wikipedia.org/wiki/Paroxetine
  3. Paroxetine. In: Wikidata. https://www.wikidata.org/wiki/Q408471
  4. Paroxetine. In: PubChem Compound. CID 43815. https://pubchem.ncbi.nlm.nih.gov/compound/43815