Chemicals and Drugs

Phenoxybenzamine

An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.

Chemical Identity

Chemical Information

Molecular Formula
C18H22ClNO
Molecular Weight
303.8 g/mol
CAS Registry No.
59-96-1
IUPAC Name
N-benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-amine
InChIKey
QZVCTJOXCFMACW-UHFFFAOYSA-N
SMILES
CC(COC1=CC=CC=C1)N(CCCl)CC2=CC=CC=C2
MeSH Unique ID
D010643
Source
PubChem CID 4768

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • Dibenylene
  • Dibenyline
  • Dibenziran
  • Dibenzylin
  • Dibenzyline
  • Dibenzyran
  • Phenoxybenzamine Hydrochloride
  • Hydrochloride, Phenoxybenzamine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

1966

MeSH Hierarchy

Tree Number

MeSH Record

NLM Classification

QV 132

AMA Style

References

  1. National Library of Medicine. Phenoxybenzamine. Medical Subject Headings (MeSH). 2026. Unique ID D010643. http://id.nlm.nih.gov/mesh/2026/D010643
  2. Phenoxybenzamine. In: Wikipedia. https://en.wikipedia.org/wiki/Phenoxybenzamine
  3. Phenoxybenzamine. In: Wikidata. https://www.wikidata.org/wiki/Q419824
  4. Phenoxybenzamine. In: PubChem Compound. CID 4768. https://pubchem.ncbi.nlm.nih.gov/compound/4768