Chemicals and Drugs

Platelet-Derived Growth Factor Receptors

Specific receptors on cell membranes that react with PLATELET-DERIVED GROWTH FACTOR, its analogs, or antagonists. The alpha PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA) and the beta PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA) are the two principle types of PDGF receptors. Activation of the protein-tyrosine kinase activity of the receptors occurs by ligand-induced dimerization or heterodimerization of PDGF receptor types.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Specific receptors on cell membranes that react with PLATELET-DERIVED GROWTH FACTOR, its analogs, or antagonists. The alpha PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA) and the beta PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA) are the two principle types of PDGF receptors. Activation of the protein-tyrosine kinase activity of the receptors occurs by ligand-induced dimerization or heterodimerization of PDGF receptor types.

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

See Also

MeSH Record

Synonyms

9 entry terms
  • PDGF Receptor
  • PDGF Receptors
  • Platelet-Derived Growth Factor Receptor
  • Receptors, PDGF
  • Receptors, Platelet-Derived Growth Factor
  • Platelet Derived Growth Factor Receptor
  • Platelet Derived Growth Factor Receptors
  • Receptor, PDGF
  • Receptors, Platelet Derived Growth Factor

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

93; was PLATELET-DERIVED GROWTH FACTOR RECEPTOR (NM) 1982-92; PLATELET DERIVED GROWTH FACTOR RECEPTOR-KINASE was NM 1989-92

MeSH Record

Previous Indexing

  • Receptors, Endogenous Substances (1982-1992)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.913w.696w.620.682w.725w.400w.900w
  2. D12.776w.476.568w.400w.900w
  3. D12.776w.543w.750w.630w.625w
  4. D12.776w.543w.750w.750w.400w.630w

AMA Style

References

  1. National Library of Medicine. Platelet-Derived Growth Factor Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D017479. http://id.nlm.nih.gov/mesh/2026/D017479
  2. Platelet-Derived Growth Factor Receptors. In: Wikipedia. https://en.wikipedia.org/wiki/Platelet-derived_growth_factor_receptor
  3. Platelet-Derived Growth Factor Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q7202242