Chemicals and Drugs

Prednisone

A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.

Chemical Identity

Chemical Information

Molecular Formula
C21H26O5
Molecular Weight
358.4 g/mol
CAS Registry No.
53-03-2
IUPAC Name
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
InChIKey
XOFYZVNMUHMLCC-ZPOLXVRWSA-N
SMILES
C[C@]12CC(=O)[C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)CCC4=CC(=O)C=C[C@]34C
MeSH Unique ID
D011241
Source
PubChem CID 5865

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

32 entry terms
  • Dehydrocortisone
  • delta-Cortisone
  • Apo-Prednisone
  • Cortan
  • Cortancyl
  • Cutason
  • Dacortin
  • Decortin
  • Decortisyl
  • Deltasone
  • Encorton
  • Encortone
  • Enkortolon
  • Kortancyl
  • Liquid Pred
  • Meticorten
  • Orasone
  • Panafcort
  • Panasol
  • Predni Tablinen
  • Prednidib
  • Predniment
  • Prednison Acsis
  • Prednison Galen
  • Prednison Hexal
  • Pronisone
  • Rectodelt
  • Sone
  • Sterapred
  • Ultracorten
  • Winpred
  • Acsis, Prednison

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

note entry term DECORTIN: DECORTIN (DESOXYCORTICOSTERONE) see DESOXYCORTICOSTERONE is also available

MeSH Record

History Note

/adv eff-pois-tox was PREDNISONE TOXICOLOGY 1963-65; /ther use was PREDNISONE, THERAPEUTIC 1965

MeSH Hierarchy

Tree Number

  1. D04w.210.500w.745.432w.719.702w

MeSH Record

NLM Classification

WK 755

AMA Style

References

  1. National Library of Medicine. Prednisone. Medical Subject Headings (MeSH). 2026. Unique ID D011241. http://id.nlm.nih.gov/mesh/2026/D011241
  2. Prednisone. In: Wikipedia. https://en.wikipedia.org/wiki/Prednisone
  3. Prednisone. In: Wikidata. https://www.wikidata.org/wiki/Q424972
  4. Prednisone. In: PubChem Compound. CID 5865. https://pubchem.ncbi.nlm.nih.gov/compound/5865