Chemicals and Drugs

Prochlorperazine

A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)

Chemical Identity

Chemical Information

Molecular Formula
C20H24ClN3S
Molecular Weight
373.9 g/mol
CAS Registry No.
58-38-8
IUPAC Name
2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
InChIKey
WIKYUJGCLQQFNW-UHFFFAOYSA-N
SMILES
CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl
MeSH Unique ID
D011346
Source
PubChem CID 4917

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • Compazine
  • Prochlorperazine Edisylate
  • Prochlorperazine Edisylate Salt
  • Prochlorperazine Maleate
  • Edisylate Salt, Prochlorperazine
  • Edisylate, Prochlorperazine
  • Maleate, Prochlorperazine
  • Salt, Prochlorperazine Edisylate

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Prochlorperazine. Medical Subject Headings (MeSH). 2026. Unique ID D011346. http://id.nlm.nih.gov/mesh/2026/D011346
  2. Prochlorperazine. In: Wikipedia. https://en.wikipedia.org/wiki/Prochlorperazine
  3. Prochlorperazine. In: Wikidata. https://www.wikidata.org/wiki/Q2359690
  4. Prochlorperazine. In: PubChem Compound. CID 4917. https://pubchem.ncbi.nlm.nih.gov/compound/4917