Chemicals and Drugs

Procyclidine

A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.

Chemical Identity

Chemical Information

Molecular Formula
C19H29NO
Molecular Weight
287.4 g/mol
CAS Registry No.
77-37-2
IUPAC Name
1-cyclohexyl-1-phenyl-3-pyrrolidin-1-ylpropan-1-ol
InChIKey
WYDUSKDSKCASEF-UHFFFAOYSA-N
SMILES
C1CCC(CC1)C(CCN2CCCC2)(C3=CC=CC=C3)O
MeSH Unique ID
D011352
Source
PubChem CID 4919

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

9 entry terms
  • Arpicolin
  • Kemadren
  • Kemadrin
  • Mucinil
  • Osnervan
  • Procyclid
  • Procyclidine Hydrochloride
  • Tricyclamol
  • Hydrochloride, Procyclidine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

a central muscle relaxant

MeSH Record

History Note

91(66); was see under PYRROLIDINES 1966-90

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Procyclidine. Medical Subject Headings (MeSH). 2026. Unique ID D011352. http://id.nlm.nih.gov/mesh/2026/D011352
  2. Procyclidine. In: Wikipedia. https://en.wikipedia.org/wiki/Procyclidine
  3. Procyclidine. In: Wikidata. https://www.wikidata.org/wiki/Q268997
  4. Procyclidine. In: PubChem Compound. CID 4919. https://pubchem.ncbi.nlm.nih.gov/compound/4919