Chemicals and Drugs

Proto-Oncogene Proteins c-raf

A ubiquitously expressed raf kinase subclass that plays an important role in SIGNAL TRANSDUCTION. The c-raf Kinases are MAP kinase kinase kinases that have specificity for MAP KINASE KINASE 1 and MAP KINASE KINASE 2.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A ubiquitously expressed raf kinase subclass that plays an important role in SIGNAL TRANSDUCTION. The c-raf Kinases are MAP kinase kinase kinases that have specificity for MAP KINASE KINASE 1 and MAP KINASE KINASE 2.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

See Also

MeSH Record

Synonyms

22 entry terms
  • Kinase Raf-1
  • Kinase p74(raf-1)
  • Proto-Oncogene Protein c-raf
  • c-raf Kinases
  • c-raf Proteins
  • cRaf1 Kinase
  • raf-1 Kinase
  • Kinase Raf 1
  • Kinase, cRaf1
  • Kinase, raf-1
  • Kinases, c-raf
  • Protein c-raf, Proto-Oncogene
  • Proteins c-raf, Proto-Oncogene
  • Proteins, c-raf
  • Proto Oncogene Protein c raf
  • Proto Oncogene Proteins c raf
  • Raf-1, Kinase
  • c raf Kinases
  • c raf Proteins
  • c-raf, Proto-Oncogene Protein
  • c-raf, Proto-Oncogene Proteins
  • raf 1 Kinase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

1998 (1986)

MeSH Record

Previous Indexing

  • Protein-Serine-Threonine Kinases (1993-1997)
  • Proto-Oncogene Proteins (1986-1997)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Proto-Oncogene Proteins c-raf. Medical Subject Headings (MeSH). 2026. Unique ID D019908. http://id.nlm.nih.gov/mesh/2026/D019908
  2. Proto-Oncogene Proteins c-raf. In: Wikipedia. https://en.wikipedia.org/wiki/C-Raf
  3. Proto-Oncogene Proteins c-raf. In: Wikidata. https://www.wikidata.org/wiki/Q410434