Chemicals and Drugs

raf Kinases

A family of closely-related serine-threonine kinases that were originally identified as the cellular homologs of the retrovirus-derived V-RAF KINASES. They are MAP kinase kinase kinases that play important roles in SIGNAL TRANSDUCTION.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of closely-related serine-threonine kinases that were originally identified as the cellular homologs of the retrovirus-derived V-RAF KINASES. They are MAP kinase kinase kinases that play important roles in SIGNAL TRANSDUCTION.

MeSH Record

Classification

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MeSH Record

Synonyms

18 entry terms
  • Proto-Oncogene Proteins raf
  • raf Kinase
  • raf MAP Kinase Kinase Kinases
  • raf Proto-Oncogene Proteins
  • raf Serine-Theonine Protein Kinases
  • Kinase, raf
  • Kinases, raf
  • Proteins raf, Proto-Oncogene
  • Proto Oncogene Proteins raf
  • Proto-Oncogene Proteins, raf
  • raf Proto Oncogene Proteins
  • raf Serine Theonine Protein Kinases
  • MIL-RAF Proteins
  • mil-raf Protein Kinases
  • Kinases, mil-raf Protein
  • MIL RAF Proteins
  • Protein Kinases, mil-raf
  • mil raf Protein Kinases

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2005

MeSH Record

Previous Indexing

  • Proto-Oncogene Proteins c-raf (1986-2004)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. raf Kinases. Medical Subject Headings (MeSH). 2026. Unique ID D048490. http://id.nlm.nih.gov/mesh/2026/D048490
  2. raf Kinases. In: Wikipedia. https://en.wikipedia.org/wiki/RAF_kinase
  3. raf Kinases. In: Wikidata. https://www.wikidata.org/wiki/Q22015156