Structured Summary
Abstract
An NAD-dependent ADP-ribosyltransferase that catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD onto elongation factor 2 (EF-2) thus arresting protein synthesis. Commonly used as the toxin in immunotoxins.
MeSH Record
Classification
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MeSH Record
Synonyms
8 entry terms
- ETA, Pseudomonas
- Exotoxin A, Pseudomonas
- Exotoxin A, Pseudomonas aeruginosa
- ToxA protein, Pseudomonas aeruginosa
- PE38QQR
- PE40 toxin
- Recombinant Truncated Pseudomonas Exotoxin A, Form PE38QQR
- Recombinant Truncated Pseudomonas Exotoxin A, Form PE40
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2024 (2022)
MeSH Hierarchy
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AMA Style
References
- National Library of Medicine. Pseudomonas aeruginosa Exotoxin A. Medical Subject Headings (MeSH). 2026. Unique ID D000097668. http://id.nlm.nih.gov/mesh/2026/D000097668
- Pseudomonas aeruginosa Exotoxin A. In: Wikipedia. https://en.wikipedia.org/wiki/Pseudomonas_exotoxin
- Pseudomonas aeruginosa Exotoxin A. In: Wikidata. https://www.wikidata.org/wiki/Q907386