Chemicals and Drugs

Pyruvate Carboxylase

A biotin-dependent enzyme belonging to the ligase family that catalyzes the addition of CARBON DIOXIDE to pyruvate. It is occurs in both plants and animals. Deficiency of this enzyme causes severe psychomotor retardation and ACIDOSIS, LACTIC in infants. EC 6.4.1.1.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A biotin-dependent enzyme belonging to the ligase family that catalyzes the addition of CARBON DIOXIDE to pyruvate. It is occurs in both plants and animals. Deficiency of this enzyme causes severe psychomotor retardation and ACIDOSIS, LACTIC in infants. EC 6.4.1.1.

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Classification

Broader headings

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Synonyms

1 entry terms
  • Carboxylase, Pyruvate

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

74

MeSH Hierarchy

Tree Number

  1. D08.811w.464w.257.500w

AMA Style

References

  1. National Library of Medicine. Pyruvate Carboxylase. Medical Subject Headings (MeSH). 2026. Unique ID D011766. http://id.nlm.nih.gov/mesh/2026/D011766
  2. Pyruvate Carboxylase. In: Wikipedia. https://en.wikipedia.org/wiki/Pyruvate_carboxylase
  3. Pyruvate Carboxylase. In: Wikidata. https://www.wikidata.org/wiki/Q21114968