Chemicals and Drugs

Receptor-Interacting Protein Serine-Threonine Kinases

A family of serine-threonine kinases that plays a role in intracellular signal transduction by interacting with a variety of signaling adaptor proteins such as CRADD SIGNALING ADAPTOR PROTEIN; TNF RECEPTOR-ASSOCIATED FACTOR 2; and TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN. Although they were initially described as death domain-binding adaptor proteins, members of this family may contain other protein-binding domains such as those involving caspase activation and recruitment.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of serine-threonine kinases that plays a role in intracellular signal transduction by interacting with a variety of signaling adaptor proteins such as CRADD SIGNALING ADAPTOR PROTEIN; TNF RECEPTOR-ASSOCIATED FACTOR 2; and TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN. Although they were initially described as death domain-binding adaptor proteins, members of this family may contain other protein-binding domains such as those involving caspase activation and recruitment.

MeSH Record

Classification

Broader headings

Narrower headings

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MeSH Record

Synonyms

17 entry terms
  • RIP Serine-Threonine Kinases
  • RIPK (Ribosome Inactivating Proteins)
  • RIPK Ribosome Inactivating Proteins
  • Kinases, RIP Serine-Threonine
  • RIP Serine Threonine Kinases
  • Receptor Interacting Protein Serine Threonine Kinases
  • Serine-Threonine Kinases, RIP
  • RIP (Receptor Interacting Protein)
  • RIP Serine-Threonine Kinase
  • Receptor Interacting Protein RIP
  • Receptor-Interacting Protein Serine-Threonine Kinase 1
  • Receptor-Interacting Protein Serine-Threonine Kinase 3
  • Kinase, RIP Serine-Threonine
  • RIP Serine Threonine Kinase
  • Receptor Interacting Protein Serine Threonine Kinase 1
  • Receptor Interacting Protein Serine Threonine Kinase 3
  • Serine-Threonine Kinase, RIP

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007(1995)

MeSH Hierarchy

Tree Numbers

  1. D08.811w.913w.696w.620.682w.700w.801
  2. D12.776w.157w.057w.018.400
  3. D12.776w.157w.057w.500w.186
  4. D12.776w.476.024w.320.662
  5. D12.776w.476.024w.500w.186
  6. D12.776w.476.075.421.400
  7. D12.776w.476.563w.801

AMA Style

References

  1. National Library of Medicine. Receptor-Interacting Protein Serine-Threonine Kinases. Medical Subject Headings (MeSH). 2026. Unique ID D053422. http://id.nlm.nih.gov/mesh/2026/D053422
  2. Receptor-Interacting Protein Serine-Threonine Kinases. In: Wikidata. https://www.wikidata.org/wiki/Q74656232