Chemicals and Drugs

Death Domain Receptor Signaling Adaptor Proteins

Intracellular signaling adaptor proteins that contain DEATH EFFECTOR DOMAINS and bind to the cytoplasmic DEATH DOMAIN region found on DEATH DOMAIN RECEPTORS. Many of the proteins in this class take part in intracellular signaling involving TUMOR NECROSIS FACTOR RECEPTORS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Intracellular signaling adaptor proteins that contain DEATH EFFECTOR DOMAINS and bind to the cytoplasmic DEATH DOMAIN region found on DEATH DOMAIN RECEPTORS. Many of the proteins in this class take part in intracellular signaling involving TUMOR NECROSIS FACTOR RECEPTORS.

MeSH Record

Classification

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See Also

MeSH Record

Synonyms

9 entry terms
  • DED Signaling Adaptor Proteins
  • Death Effector Domain Signaling Adaptor Proteins
  • Death Inducing Signaling Complex Proteins
  • DISC (Death Inducing Signaling Complex)
  • Death Effector Domain Containing Proteins
  • Fas-DISC Components
  • fas Death-Inducing Signaling Complex Components
  • Fas DISC Components
  • fas Death Inducing Signaling Complex Components

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007(2002)

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Tree Numbers

AMA Style

References

  1. National Library of Medicine. Death Domain Receptor Signaling Adaptor Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D053418. http://id.nlm.nih.gov/mesh/2026/D053418
  2. Death Domain Receptor Signaling Adaptor Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q77040033