Chemicals and Drugs

Replication Protein C

A DNA-binding protein and AAA ATPase that consists of 5 polypeptides and plays an essential role in DNA REPLICATION in eukaryotes. It binds DNA PRIMER-template junctions and recruits PROLIFERATING CELL NUCLEAR ANTIGEN and DNA POLYMERASES to the site of DNA synthesis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A DNA-binding protein and AAA ATPase that consists of 5 polypeptides and plays an essential role in DNA REPLICATION in eukaryotes. It binds DNA PRIMER-template junctions and recruits PROLIFERATING CELL NUCLEAR ANTIGEN and DNA POLYMERASES to the site of DNA synthesis.

MeSH Record

Classification

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MeSH Record

Synonyms

18 entry terms
  • Activator 1 Protein
  • Replication Factor C
  • Activator 1 Protein, 145 kDa Subunit
  • Activator 1 Protein, 36 kDa Subunit
  • Activator 1 Protein, 37 kDa Subunit
  • Activator 1 Protein, 38 kDa Subunit
  • Activator 1 Protein, 40 kDa Subunit
  • Activator 1 p40
  • Replication Factor C, Subunit 1
  • Replication Factor C, Subunit 2
  • Replication Factor C, Subunit 3
  • Replication Factor C, Subunit 4
  • Replication Factor C, Subunit 5
  • Replication Protein C, Subunit 1
  • Replication Protein C, Subunit 2
  • Replication Protein C, Subunit 3
  • Replication Protein C, Subunit 4
  • Replication Protein C, Subunit 5

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1992)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Replication Protein C. Medical Subject Headings (MeSH). 2026. Unique ID D051818. http://id.nlm.nih.gov/mesh/2026/D051818
  2. Replication Protein C. In: Wikidata. https://www.wikidata.org/wiki/Q24741739