Chemicals and Drugs

Riluzole

A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.

Chemical Identity

Chemical Information

Molecular Formula
C8H5F3N2OS
Molecular Weight
234.20 g/mol
CAS Registry No.
1744-22-5
IUPAC Name
6-(trifluoromethoxy)-1,3-benzothiazol-2-amine
InChIKey
FTALBRSUTCGOEG-UHFFFAOYSA-N
SMILES
C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)N
MeSH Unique ID
D019782
Source
PubChem CID 5070

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

9 entry terms
  • 2-Amino-6-trifluoromethoxybenzothiazole
  • 2 Amino 6 trifluoromethoxybenzothiazole
  • PK-26124
  • RP-54274
  • Rilutek
  • PK 26124
  • PK26124
  • RP 54274
  • RP54274

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

98; use RILUZOLE (NM) 1986-97

MeSH Record

Previous Indexing

  • Thiazoles (1986-1997)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Riluzole. Medical Subject Headings (MeSH). 2026. Unique ID D019782. http://id.nlm.nih.gov/mesh/2026/D019782
  2. Riluzole. In: Wikipedia. https://en.wikipedia.org/wiki/Riluzole
  3. Riluzole. In: Wikidata. https://www.wikidata.org/wiki/Q415744
  4. Riluzole. In: PubChem Compound. CID 5070. https://pubchem.ncbi.nlm.nih.gov/compound/5070