Chemicals and Drugs

Scopolamine

An alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics like ATROPINE, but may have more central nervous system effects. Its many uses include an anesthetic premedication, the treatment of URINARY INCONTINENCE and MOTION SICKNESS, an antispasmodic, and a mydriatic and cycloplegic.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics like ATROPINE, but may have more central nervous system effects. Its many uses include an anesthetic premedication, the treatment of URINARY INCONTINENCE and MOTION SICKNESS, an antispasmodic, and a mydriatic and cycloplegic.

Chemical Identity

Chemical Information

Molecular Formula
C17H21NO4
Molecular Weight
303.35 g/mol
CAS Registry No.
51-34-3
IUPAC Name
[(1R,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl] (2S)-3-hydroxy-2-phenylpropanoate
InChIKey
STECJAGHUSJQJN-MKXJHAPZSA-N
SMILES
CN1[C@@H]2CC(C[C@H]1C3C2O3)OC(=O)[C@H](CO)C4=CC=CC=C4
MeSH Unique ID
D012601
Source
PubChem CID 153311

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

15 entry terms
  • Hyoscine
  • Boro-Scopol
  • Isopto Hyoscine
  • Kwells
  • Scoburen
  • Scopace
  • Scopoderm TTS
  • Scopolamine Cooper
  • Scopolamine Hydrobromide
  • Transderm Scop
  • Transderm-V
  • Travacalm HO
  • Vorigeno
  • Boro Scopol
  • Transderm V

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1966)

MeSH Hierarchy

Tree Numbers

  1. D02w.145.074.722.822.775w
  2. D03w.132w.760.180.848w
  3. D03w.132w.889.601.775w
  4. D03w.605.084.500.722.822.775w
  5. D03w.605.869.822.775w

MeSH Record

NLM Classification

QV 134

AMA Style

References

  1. National Library of Medicine. Scopolamine. Medical Subject Headings (MeSH). 2026. Unique ID D012601. http://id.nlm.nih.gov/mesh/2026/D012601
  2. Scopolamine. In: Wikipedia. https://en.wikipedia.org/wiki/Scopolamine
  3. Scopolamine. In: Wikidata. https://www.wikidata.org/wiki/Q337188
  4. Scopolamine. In: PubChem Compound. CID 153311. https://pubchem.ncbi.nlm.nih.gov/compound/153311