Structured Summary
Abstract
A selective, irreversible inhibitor of Type B monoamine oxidase that is used for the treatment of newly diagnosed patients with PARKINSON DISEASE, and for the treatment of depressive disorders. The compound without isomeric designation is Deprenyl.
Chemical Identity
Chemical Information
- Molecular Formula
- C13H17N
- Molecular Weight
- 187.28 g/mol
- CAS Registry No.
- 2323-36-6
- IUPAC Name
- N-methyl-1-phenyl-N-prop-2-ynylpropan-2-amine
- InChIKey
- MEZLKOACVSPNER-UHFFFAOYSA-N
- SMILES
- CC(CC1=CC=CC=C1)N(C)CC#C
- MeSH Unique ID
- D012642
- Source
- PubChem CID 5195
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
21 entry terms
- L-Deprenyl
- Selegiline, (R)-Isomer
- Selegyline
- Deprenalin
- Deprenil
- Deprenyl
- E-250
- Eldepryl
- Emsam
- Humex
- Jumex
- Selegiline Hydrochloride
- Selegiline Hydrochloride, (R)-Isomer
- Selegiline Hydrochloride, (R,S)-Isomer
- Selegiline Hydrochloride, (S)-Isomer
- Selegiline, (R,S)-Isomer
- Selegiline, (S)-Isomer
- Yumex
- Zelapar
- E 250
- E250
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
91(84); was see under PHENETHYLAMINES 1984-90; was DEPRENYL see under PHENETHYLAMINES 1979-83
MeSH Record
Previous Indexing
- Monoamine Oxidase Inhibitors (1966-1978)
- Phenethylamines (1966-1978)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Selegiline. Medical Subject Headings (MeSH). 2026. Unique ID D012642. http://id.nlm.nih.gov/mesh/2026/D012642
- Selegiline. In: Wikipedia. https://en.wikipedia.org/wiki/Deprenyl
- Selegiline. In: Wikidata. https://www.wikidata.org/wiki/Q402633
- Selegiline. In: PubChem Compound. CID 5195. https://pubchem.ncbi.nlm.nih.gov/compound/5195