Structured Summary
Abstract
A serotonin receptor subtype that is localized to the CAUDATE NUCLEUS; PUTAMEN; the NUCLEUS ACCUMBENS; the HIPPOCAMPUS, and the RAPHE NUCLEI. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1B RECEPTOR, but is expressed at low levels. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigrane effect.
MeSH Record
Classification
Broader headings
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MeSH Record
Synonyms
18 entry terms
- 5-HT(1D) Receptor
- 5-HT1D Receptor
- 5-Hydroxytryptamine1D Receptor
- Receptor, Serotonin 1D
- Receptor, Serotonin, 5-HT1D
- Serotonin 1D Receptor
- Serotonin 1D Receptors
- 5 HT1D Receptor
- 5 Hydroxytryptamine1D Receptor
- Receptor, 5-HT1D
- Receptor, 5-Hydroxytryptamine1D
- Receptors, Serotonin 1D
- 5-HT(1Dalpha) Receptor
- 5-HT1Dalpha Receptor
- Receptor, Serotonin 1Dalpha
- Serotonin 1D Alpha Receptor
- Serotonin 1Dalpha Receptor
- Serotonin 1Dalpha Receptors
MeSH Record
Aspects Covered
17 allowable subheadings
Indexed with the subheadings administration & dosage, analysis, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.
MeSH Record
History Note
2004; use RECEPTOR, SEROTONIN, 5-HT1D (NM) 1996-2003
MeSH Record
Previous Indexing
- Receptors, Serotonin (1996-2003)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Serotonin 5-HT1D Receptor. Medical Subject Headings (MeSH). 2026. Unique ID D044346. http://id.nlm.nih.gov/mesh/2026/D044346
- Serotonin 5-HT1D Receptor. In: Wikidata. https://www.wikidata.org/wiki/Q24774023