Chemicals and Drugs

Serotonin 5-HT1F Receptor

A serotonin receptor subtype found in the GLOBUS PALLIDUS; HIPPOCAMPUS; PUTAMEN; SUBSTANTIA NIGRA; and TRIGEMINAL NUCLEUS, SPINAL that can modulate the release of CALCITONIN GENE-RELATED PEPTIDE from these nerves. Unlike 5-HT1B RECEPTORS, the activation of 5-HT1F receptors does not cause VASOCONSTRICTION. 5-HT1F receptor antagonists are used for the treatment of MIGRAINE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A serotonin receptor subtype found in the GLOBUS PALLIDUS; HIPPOCAMPUS; PUTAMEN; SUBSTANTIA NIGRA; and TRIGEMINAL NUCLEUS, SPINAL that can modulate the release of CALCITONIN GENE-RELATED PEPTIDE from these nerves. Unlike 5-HT1B RECEPTORS, the activation of 5-HT1F receptors does not cause VASOCONSTRICTION. 5-HT1F receptor antagonists are used for the treatment of MIGRAINE.

MeSH Record

Classification

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MeSH Record

Synonyms

13 entry terms
  • Receptor, Serotonin, 5-HT1F
  • Receptors, Serotonin 5-HT1F
  • 5-HT1F Receptors, Serotonin
  • Receptors, Serotonin 5 HT1F
  • Serotonin 5-HT1F Receptors
  • 5-HT(1F) Receptor
  • 5-HT1F Receptor
  • Receptor, Serotonin 1F
  • Serotonin 1F Receptor
  • Serotonin 1F Receptors
  • 5 HT1F Receptor
  • Receptor, 5-HT1F
  • Receptors, Serotonin 1F

MeSH Record

Aspects Covered

17 allowable subheadings

Indexed with the subheadings administration & dosage, analysis, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2024 (1997)

MeSH Record

Previous Indexing

  • Receptors, Serotonin (1997-2023)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Serotonin 5-HT1F Receptor. Medical Subject Headings (MeSH). 2026. Unique ID D000096642. http://id.nlm.nih.gov/mesh/2026/D000096642
  2. Serotonin 5-HT1F Receptor. In: Wikidata. https://www.wikidata.org/wiki/Q24745922