Chemicals and Drugs

Serotonin 5-HT2A Receptor

A serotonin receptor subtype found widely distributed in peripheral tissues where it mediates the contractile responses of variety of tissues that contain SMOOTH MUSCLE. Selective 5-HT2A receptor antagonists include KETANSERIN. The 5-HT2A subtype is also located in BASAL GANGLIA and CEREBRAL CORTEX of the BRAIN where it mediates the effects of HALLUCINOGENS such as LSD.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A serotonin receptor subtype found widely distributed in peripheral tissues where it mediates the contractile responses of variety of tissues that contain SMOOTH MUSCLE. Selective 5-HT2A receptor antagonists include KETANSERIN. The 5-HT2A subtype is also located in BASAL GANGLIA and CEREBRAL CORTEX of the BRAIN where it mediates the effects of HALLUCINOGENS such as LSD.

MeSH Record

Classification

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

9 entry terms
  • 5-HT(2A) Receptor
  • 5-HT2A Receptor
  • Receptor, Serotonin 2A
  • Receptor, Serotonin, 5-HT2A
  • Serotonin 2A Receptor
  • Serotonin 2A Receptors
  • 5 HT2A Receptor
  • Receptor, 5-HT2A
  • Receptors, Serotonin 2A

MeSH Record

Aspects Covered

17 allowable subheadings

Indexed with the subheadings administration & dosage, analysis, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2004; use RECEPTOR, SEROTONIN, 5-HT2A (NM) 1994-2003

MeSH Record

Previous Indexing

  • Receptors, Serotonin (1994-2003)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Serotonin 5-HT2A Receptor. Medical Subject Headings (MeSH). 2026. Unique ID D044402. http://id.nlm.nih.gov/mesh/2026/D044402
  2. Serotonin 5-HT2A Receptor. In: Wikidata. https://www.wikidata.org/wiki/Q24575295