Structured Summary
Abstract
A mixture of flavonoids extracted from seeds of the MILK THISTLE, Silybum marianum. It consists primarily of silybin and its isomers, silicristin and silidianin. Silymarin displays antioxidant and membrane stabilizing activity. It protects various tissues and organs against chemical injury, and shows potential as an antihepatoxic agent.
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Classification
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Drug Class
Pharmacological Action
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See Also
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Synonyms
4 entry terms
- Silimarin
- Carsil
- Karsil
- Legalon
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Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
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History Note
91(75); was see under FLAVONES 1975-90
MeSH Record
Previous Indexing
- Alcohols (1971-1974)
- Flavones (1971-1974)
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Tree Numbers
AMA Style
References
- National Library of Medicine. Silymarin. Medical Subject Headings (MeSH). 2026. Unique ID D012838. http://id.nlm.nih.gov/mesh/2026/D012838
- Silymarin. In: Wikidata. https://www.wikidata.org/wiki/Q60970556