Anatomy

Somatostatin-Secreting Cells

Endocrine cells found throughout the GASTROINTESTINAL TRACT and in islets of the PANCREAS. D cells secrete SOMATOSTATIN that acts in both an endocrine and paracrine manner. Somatostatin acts on a variety of tissues including the PITUITARY GLAND; gastrointestinal tract; pancreas; and KIDNEY by inhibiting the release of hormones, such as GROWTH HORMONE; GASTRIN; INSULIN; and RENIN.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Endocrine cells found throughout the GASTROINTESTINAL TRACT and in islets of the PANCREAS. D cells secrete SOMATOSTATIN that acts in both an endocrine and paracrine manner. Somatostatin acts on a variety of tissues including the PITUITARY GLAND; gastrointestinal tract; pancreas; and KIDNEY by inhibiting the release of hormones, such as GROWTH HORMONE; GASTRIN; INSULIN; and RENIN.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

23 entry terms
  • D Cells
  • Somatostatin Cells
  • delta Cells
  • D Cell
  • Somatostatin Cell
  • Somatostatin Secreting Cells
  • Somatostatin-Secreting Cell
  • delta Cell
  • Gastric D Cells
  • Gastric delta Cells
  • Pancreatic D Cells
  • Pancreatic delta Cells
  • D Cell, Gastric
  • D Cells, Gastric
  • D Cells, Pancreatic
  • Gastric D Cell
  • Gastric delta Cell
  • Pancreatic D Cell
  • Pancreatic delta Cell
  • delta Cell, Gastric
  • delta Cell, Pancreatic
  • delta Cells, Gastric
  • delta Cells, Pancreatic

MeSH Record

Aspects Covered

15 allowable subheadings

Indexed with the subheadings chemistry, classification, cytology, drug effects, enzymology, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.

MeSH Record

Indexing Annotation

/transpl: if from pancreas, coordinate with ISLETS OF LANGERHANS TRANSPLANTATION

MeSH Record

History Note

2006 (1998); for PANCREATIC DELTA CELLS use ISLETS OF LANGERHANS 1991-1997

MeSH Record

Previous Indexing

  • Gastric Mucosa (1976-1997)
  • Islets of Langerhans (1966-1997)
  • Pancreas/cytology (1968-1989)

MeSH Hierarchy

Tree Numbers

  1. A03w.556w.875.875w.440w.854
  2. A03w.734w.414w.793
  3. A06w.300w.414w.793
  4. A06w.390w.825
  5. A10w.615w.550w.291w.825
  6. A11w.382.625w.950
  7. A11w.436.294w.950

AMA Style

References

  1. National Library of Medicine. Somatostatin-Secreting Cells. Medical Subject Headings (MeSH). 2026. Unique ID D019864. http://id.nlm.nih.gov/mesh/2026/D019864
  2. Somatostatin-Secreting Cells. In: Wikidata. https://www.wikidata.org/wiki/Q70229756