Structured Summary
Abstract
A highly conserved, non-selective TRP cation channel that contains 14-17 ANKYRIN REPEATS. It functions in cold sensation and NOCICEPTION of endogenous inflammatory factors and volatile irritants. TRPA1 is also activated by CANNABINOIDS and may play a role in sound perception by hair cells of the inner ear.
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Classification
Broader headings
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Synonyms
5 entry terms
- TRPA1 Channel
- Transient Receptor Potential Cation Channel Subfamily A, Member 1
- Cation Channel, TRPA1
- Channel, TRPA1
- Channel, TRPA1 Cation
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2018
MeSH Record
Previous Indexing
- Calcium Channels (2003-2017)
- Nerve Tissue Proteins (2003-2017)
- Transient Receptor Potential Channels (2006-2017)
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AMA Style
References
- National Library of Medicine. TRPA1 Cation Channel. Medical Subject Headings (MeSH). 2026. Unique ID D000074025. http://id.nlm.nih.gov/mesh/2026/D000074025
- TRPA1 Cation Channel. In: Wikidata. https://www.wikidata.org/wiki/Q7834290