Structured Summary
Abstract
A Janus kinase subtype that is involved in signaling from a broad variety of CYTOKINE RECEPTORS. The TYK2 kinase is considered the founding member of the janus kinase family and was initially discovered as a signaling partner for the INTERFERON ALPHA-BETA RECEPTOR. The kinase has since been shown to signal from several INTERLEUKIN RECEPTORS.
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Synonyms
4 entry terms
- Non-Receptor Tyrosine-Protein Kinase TYK2
- Tyrosine Kinase 2
- Kinase, TYK2
- Non Receptor Tyrosine Protein Kinase TYK2
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Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
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History Note
2007
MeSH Record
Previous Indexing
- Protein-Tyrosine Kinase (1991-2006)
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AMA Style
References
- National Library of Medicine. TYK2 Kinase. Medical Subject Headings (MeSH). 2026. Unique ID D053634. http://id.nlm.nih.gov/mesh/2026/D053634
- TYK2 Kinase. In: Wikidata. https://www.wikidata.org/wiki/Q7861688