Anatomy

T Follicular Helper Cells

A specialized subpopulation of CD4+ T cells involved in formation of GERMINAL CENTER. Tfh cells are mostly located in secondary lymphoid organs, e.g., TONSIL; SPLEEN and LYMPH NODES. They are CD4 ANTIGEN; CD45 ANTIGEN; B-CELL LYMPHOMA 6 PROTEIN; CXCR5 RECEPTORS; ICOS INDUCIBLE T-CELL CO-STIMULATOR; and PD1 RECEPTOR positive.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A specialized subpopulation of CD4+ T cells involved in formation of GERMINAL CENTER. Tfh cells are mostly located in secondary lymphoid organs, e.g., TONSIL; SPLEEN and LYMPH NODES. They are CD4 ANTIGEN; CD45 ANTIGEN; B-CELL LYMPHOMA 6 PROTEIN; CXCR5 RECEPTORS; ICOS INDUCIBLE T-CELL CO-STIMULATOR; and PD1 RECEPTOR positive.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

4 entry terms
  • Follicular B Helper T Cells
  • Follicular Helper T Cells
  • Tfh Cells
  • Tfh Cell

MeSH Record

Aspects Covered

15 allowable subheadings

Indexed with the subheadings chemistry, classification, cytology, drug effects, enzymology, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.

MeSH Record

History Note

2021

MeSH Record

Previous Indexing

  • T-Lymphocytes, Helper-Inducer(2004-2020)

MeSH Hierarchy

Tree Numbers

  1. A11w.118w.637w.555w.567w.550.500.400.450w
  2. A11w.118w.637w.555w.567w.569w.200w.400.450w
  3. A11w.118w.637w.555w.567w.569w.500.400.450w
  4. A15.145w.229w.637w.555w.567w.550.500.400.250w
  5. A15.145w.229w.637w.555w.567w.569w.200w.400.250w
  6. A15.382w.490w.555w.567w.550.500.400.450w
  7. A15.382w.490w.555w.567w.569w.200w.400.450w
  8. A15.382w.490w.555w.567w.569w.500.400.450w

AMA Style

References

  1. National Library of Medicine. T Follicular Helper Cells. Medical Subject Headings (MeSH). 2026. Unique ID D000084522. http://id.nlm.nih.gov/mesh/2026/D000084522
  2. T Follicular Helper Cells. In: Wikipedia. https://en.wikipedia.org/wiki/Follicular_B_helper_T_cells
  3. T Follicular Helper Cells. In: Wikidata. https://www.wikidata.org/wiki/Q5464650