Chemicals and Drugs

Tachykinins

A family of biologically active peptides sharing a common conserved C-terminal sequence, -Phe-X-Gly-Leu-Met-NH2, where X is either an aromatic or a branched aliphatic amino acid. Members of this family have been found in mammals, amphibians, and mollusks. Tachykinins have diverse pharmacological actions in the central nervous system and the cardiovascular, genitourinary, respiratory, and gastrointestinal systems, as well as in glandular tissues. This diversity of activity is due to the existence of three or more subtypes of tachykinin receptors.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of biologically active peptides sharing a common conserved C-terminal sequence, -Phe-X-Gly-Leu-Met-NH2, where X is either an aromatic or a branched aliphatic amino acid. Members of this family have been found in mammals, amphibians, and mollusks. Tachykinins have diverse pharmacological actions in the central nervous system and the cardiovascular, genitourinary, respiratory, and gastrointestinal systems, as well as in glandular tissues. This diversity of activity is due to the existence of three or more subtypes of tachykinin receptors.

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

See Also

MeSH Record

Synonyms

1 entry terms
  • Tachykinin

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

general or unspecified; prefer specifics

MeSH Record

History Note

89; PHYSALAEMIN was see under KININS 1977-88

MeSH Record

Previous Indexing

  • Kinins (1966-1988)
  • Nerve Tissue Proteins (1966-1988)
  • Neuropeptides (1987-1988)
  • Oligopeptides (1966-1988)
  • Peptides (1966-1988)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.276.812w.900w
  2. D12.644w.400w.800w
  3. D12.644w.456w.800w
  4. D12.776w.467.812w.900w
  5. D12.776w.631w.650w.800w
  6. D23.469.050w.375w.850w
  7. D23.529.812w.900w

AMA Style

References

  1. National Library of Medicine. Tachykinins. Medical Subject Headings (MeSH). 2026. Unique ID D015320. http://id.nlm.nih.gov/mesh/2026/D015320
  2. Tachykinins. In: Wikipedia. https://en.wikipedia.org/wiki/Tachykinin_peptides
  3. Tachykinins. In: Wikidata. https://www.wikidata.org/wiki/Q24720691