Chemicals and Drugs

Tazobactam Drug Combination Piperacillin

An antibiotic combination product of piperacillin and tazobactam, a penicillanic acid derivative with enhanced beta-lactamase inhibitory activity, that is used for the intravenous treatment of intra-abdominal, pelvic, and skin infections and for community-acquired pneumonia of moderate severity. It is also used for the treatment of PSEUDOMONAS AERUGINOSA INFECTIONS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An antibiotic combination product of piperacillin and tazobactam, a penicillanic acid derivative with enhanced beta-lactamase inhibitory activity, that is used for the intravenous treatment of intra-abdominal, pelvic, and skin infections and for community-acquired pneumonia of moderate severity. It is also used for the treatment of PSEUDOMONAS AERUGINOSA INFECTIONS.

Chemical Identity

Chemical Information

Molecular Formula
C33H39N9O12S2
Molecular Weight
817.9 g/mol
IUPAC Name
(2S,5R,6R)-6-[[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;(2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
InChIKey
LITBAYYWXZOHAW-XDZRHBBOSA-N
SMILES
CCN1CCN(C(=O)C1=O)C(=O)N[C@H](C2=CC=CC=C2)C(=O)N[C@H]3[C@@H]4N(C3=O)[C@H](C(S4)(C)C)C(=O)O.C[C@@]1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)O)CN3C=CN=N3
MeSH Unique ID
D000077725
Source
PubChem CID 9918881

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

13 entry terms
  • Piperacillin - Tazobactam
  • Piperacillin, Tazobactam Drug Combination
  • Piperacillin-Tazobactam Combination Product
  • Piperacillin Tazobactam
  • Piperacillin Tazobactam Combination Product
  • Tazobactam, Piperacillin -
  • Pipercillin Sodium - Tazobactam Sodium
  • Pipercillin Sodium, Tazobactam Sodium Drug Combination
  • Tazocel
  • Tazocillin
  • Tazocin
  • Zosyn
  • Pipercillin Sodium Tazobactam Sodium

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1994)

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.589w.099w.750w.687.750w.500w
  2. D02w.065w.589w.099w.750w.750w.050w.650w.500w
  3. D02w.886w.108w.750w.687.750w.500w
  4. D02w.886w.108w.750w.750w.050w.650w.500w
  5. D02w.886w.590w.841w.500w
  6. D03w.633.100.300w.750w.687.750w.500w
  7. D03w.633.100.300w.750w.750w.050w.650w.500w
  8. D26.310w.625w

AMA Style

References

  1. National Library of Medicine. Tazobactam Drug Combination Piperacillin. Medical Subject Headings (MeSH). 2026. Unique ID D000077725. http://id.nlm.nih.gov/mesh/2026/D000077725
  2. Tazobactam Drug Combination Piperacillin. In: Wikipedia. https://en.wikipedia.org/wiki/Piperacillin/tazobactam
  3. Tazobactam Drug Combination Piperacillin. In: Wikidata. https://www.wikidata.org/wiki/Q7197337
  4. Tazobactam Drug Combination Piperacillin. In: PubChem Compound. CID 9918881. https://pubchem.ncbi.nlm.nih.gov/compound/9918881