Structured Summary
Abstract
A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. This piperazine phenothiazine does not prevent vertigo or motion sickness. (From AMA Drug Evaluations Annual, 1994, p457)
Chemical Identity
Chemical Information
- Molecular Formula
- C22H29N3S2
- Molecular Weight
- 399.6 g/mol
- CAS Registry No.
- 1420-55-9
- IUPAC Name
- 2-ethylsulfanyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
- InChIKey
- XCTYLCDETUVOIP-UHFFFAOYSA-N
- SMILES
- CCSC1=CC2=C(C=C1)SC3=CC=CC=C3N2CCCN4CCN(CC4)C
- MeSH Unique ID
- D013847
- Source
- PubChem CID 5440
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
4 entry terms
- Norzine
- Thiethylperazine Malate
- Thiethylperazine Maleate (2:1)
- Torecan
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
65(63)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Thiethylperazine. Medical Subject Headings (MeSH). 2026. Unique ID D013847. http://id.nlm.nih.gov/mesh/2026/D013847
- Thiethylperazine. In: Wikipedia. https://en.wikipedia.org/wiki/Thiethylperazine
- Thiethylperazine. In: Wikidata. https://www.wikidata.org/wiki/Q372725
- Thiethylperazine. In: PubChem Compound. CID 5440. https://pubchem.ncbi.nlm.nih.gov/compound/5440